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MYP_134650
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Basic Information
Cathelicidin-BF (Cathelicidin-related protein; Snakes, reptiles, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C176H290N48O35
Standard
Sequence
KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF
Physicochemical Analysis
3638.49 Da
11.79
10.75
10.54
0.3585
-0.54
0.90
-0.26
9.34
71.33
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1387.28
-6.76
50.0
46.0
129.0
259.0
7.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0189470 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Bungarus fasciatus [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa ATCC 278953
1.2 μM
MIC
PaperSnake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics.
RECORD: Rec_0189478 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecium IS/DR
150 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0189974 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. aureus ATCC25923
400 μg/mL
MIC
PMID18795096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0216679 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Saccharibacillus kuerlensis
4.7 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
RECORD: Rec_0222186 VERIFIED: YES
Provenance & Taxonomy
Bungarus fasciatus [Animal]
Cathelicidin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
pumilus
9.4 μg/mL
MIC
PaperIdentification and characterization of novel reptile cathelicidins from elapid snakes. Peptides. 2008 Oct;29(10):1685-1691. doi: 10.1016/j.peptides.2008.06.008. PMID: 18620012. PMID18795096;18620012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18795096/
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