Peptide Database

Peptide NamePhylloseptin-H2 (PLS-H2) (Phylloseptin-2) (PS-2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC344H538N86O107S2

DescriptionStandard

        MAFLKKSLFLVLFLGLATLSICEEEKRETEEEEYNQEEDDKSEEKRFLSLIPHAINAVSTLVHHFG
    

Molecular Weight7654.59 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-7.22

Net Charge (pH 7.4) -7.63

Charge Density (pH 7.0) -0.1094

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index62.12

Aliphatic Index 96.06

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3119.51

LogP -24.31

H-bond Donors 107.0

H-bond Acceptors 105.0

Rotatable Bonds 264.0

Heavy Atoms 539.0

Ring Count 10.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176831 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Hemolytic

TargetNo Target Organism Found