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MYP_134582
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Basic Information
Apelin-28
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
28 amino acids
C144H229N53O33S
Standard
Sequence
TGPGAWQGGRRKFRRQRPRLSHKGPMPF
Physicochemical Analysis
3262.76 Da
12.00
7.48
7.24
0.2673
-1.52
0.75
-0.43
85.27
17.50
0.1071
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1408.41
-15.59
51.0
43.0
104.0
231.0
9.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036752 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Apelin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Feeding regulator
response to T-cell receptor
Mammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour
PMID26611206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26611206/
RECORD: Rec_0079082 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Apelin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Feeding regulator
the regulation of cardiac precursor cell
Mammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour
PMID26611206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26611206/
RECORD: Rec_0141045 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Apelin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Feeding regulator
apelin receptor
Mammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour
PMID11359874;26611206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11359874/
RECORD: Rec_0226277 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0234276 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Apelin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory Feeding regulator
Mammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour
PMID11359874;28890073 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11359874/
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