Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC341H541N87O94S10

DescriptionStandard

        MRTFLFLFAVLFFLTPAKNAFFDERCQRLKGTCTDYCKKNEEIIALCQKSLKCCLTMQPCGKMTED
    

Molecular Weight7684.12 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.10

Charge Density (pH 7.0) 0.0370

GRAVY Index0.01

Hydrophobic Moment 0.48

Boman Index0.00

Instability Index33.33

Aliphatic Index 69.55

Aromaticity 0.1212

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2943.47

LogP -23.80

H-bond Donors 108.0

H-bond Acceptors 107.0

Rotatable Bonds 260.0

Heavy Atoms 532.0

Ring Count 10.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177964 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence