Peptide Database

Peptide NameCecropin-A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC286H461N75O68S

DescriptionStandard

        IFFFVFACLLALSAVSAAPEPRWKVFKKIEKVGRNVRDGIIKAGPAIGVLGQAKALG
    

Molecular Weight6070.25 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.52

Charge Density (pH 7.0) 0.1009

GRAVY Index0.62

Hydrophobic Moment 0.91

Boman Index0.24

Instability Index41.12

Aliphatic Index 114.74

Aromaticity 0.1053

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2262.70

LogP -13.81

H-bond Donors 79.0

H-bond Acceptors 75.0

Rotatable Bonds 200.0

Heavy Atoms 430.0

Ring Count 10.0

Amide Bonds 58.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0231521 VERIFIED: NO

Provenance & Taxonomy

OrganismSpodoptera litura [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria