Peptide Database

Peptide NameGI-20EF

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC117H190N34O29

DescriptionStandard

        GIKEFKREFQRIKDFLRNLV
    

Molecular Weight2536.97 Da

Isoelectric Point (pI)10.27

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1382

GRAVY Index-0.69

Hydrophobic Moment 0.94

Boman Index-0.30

Instability Index17.58

Aliphatic Index 92.50

Aromaticity 0.1500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1078.06

LogP -6.67

H-bond Donors 38.0

H-bond Acceptors 32.0

Rotatable Bonds 91.0

Heavy Atoms 180.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0385688 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targeted Human Immunodeficiency Virus Type 1 HIV-1

Activity0.91 μM

MethodEC50

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3