Peptide Database

Peptide NameD4K, K16A,L18K

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC106H176N28O26S

DescriptionStandard

        GIWKTIKSMGKVFAGAIKQNL
    

Molecular Weight2290.77 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1789

GRAVY Index0.17

Hydrophobic Moment 0.67

Boman Index0.18

Instability Index-3.48

Aliphatic Index 97.62

Aromaticity 0.0952

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 891.83

LogP -6.38

H-bond Donors 31.0

H-bond Acceptors 31.0

Rotatable Bonds 80.0

Heavy Atoms 161.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016307 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans

RECORD: Rec_0021370 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

Targethuman RBCs

Activity200 μM

MethodLC50

RECORD: Rec_0083807 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetAcinetobacter baumannii

Activity6.25 μM

MethodMIC

RECORD: Rec_0371893 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli

Activity12.5 μM

MethodMIC

RECORD: Rec_0417898 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus

Activity100 μM

MethodMIC