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MYP_134386
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Basic Information
Pardaxin P-4 (1-22)
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C117H188N24O27
Standard
Sequence
GFFALIPKIISSPLFKTLLSAV
Physicochemical Analysis
2362.89 Da
10.00
1.76
1.55
0.0799
1.38
0.50
0.52
26.27
146.36
0.1364
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
789.80
-2.41
27.0
29.0
74.0
168.0
5.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0284716 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
[NH(CH 2 ) 2 NH 2 ] 2
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8620888/ PMID8620888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8620888/
RECORD: Rec_0307887 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
7.8 μg/mL
MBC
PMID8620888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8620888/
RECORD: Rec_0312601 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 27.3%, C 22.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0324792 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
31.3 μg/mL
MIC
PMID8620888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8620888/
RECORD: Rec_0334083 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
7.8 μg/mL
MIC
PMID8620888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8620888/
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