Peptide Database

Peptide NameIndolicidin [R12P][R13P]

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC98H121N19O14

DescriptionStandard

        ILPWKWPWWPWPP
    

Molecular Weight1789.13 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index-0.62

Hydrophobic Moment 0.14

Boman Index0.43

Instability Index47.03

Aliphatic Index 60.00

Aromaticity 0.3846

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 473.54

LogP 6.59

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 38.0

Heavy Atoms 131.0

Ring Count 15.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384232 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyIndolicidin

Tax ID9913

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Integrase inhibition

Activity16 μM

MethodIC50

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