Peptide Database

Peptide NameHNH endonuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length292 amino acids

Chemical FormulaC1472H2240N394O429S7

DescriptionStandard

        MPGRDEHWLEDELRRKGWVGETATTRVRFFWRPDIHGKMQVYGVHTGEGTPYEGVRAANMVWDPNIQGYSFTPSPDVDGPTITWTPEKPEGAEPIAHTGSPVKPIDQPTILIYPIPEDNADTTTPPFPVPDEHDFNYWILVFPDGSEIKPIYVYLQSARDKPGVVTGKGEVLSGGGKWLEAASAGLGAPVPAQVADKLRGQKFERFDDFREAFWLAVAECPELMEQFSPANKALIKKGRSPYAVPKEQSGGRTVFEIHHKIRIVDGGSVYDIENMSIATPKRHIMLHSKEVS
    

Molecular Weight32544.37 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-8.67

Net Charge (pH 7.4) -9.44

Charge Density (pH 7.0) -0.0297

GRAVY Index-0.51

Hydrophobic Moment 0.63

Boman Index0.01

Instability Index47.15

Aliphatic Index 70.10

Aromaticity 0.0993

Extinction Coeff. Reduced 57410.00

Extinction Coeff. Oxidized 57410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0266890 VERIFIED: YES

Provenance & Taxonomy

OrganismCandidatus Symbiopectobacterium sp. Dall1.0 [Bacterium]

FamilyPyocin/Colicin

Tax ID2794577

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli