Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC438H712N130O114S10

DescriptionStandard

        MKLPLLVLAALGFLAQMAPAHGGRTRCGRALPGHCRLYCHKKEQTMFMCDRYKQCCVLSNFLPEPVVSPYRSLPKSSNIKNTIKHKNQ
    

Molecular Weight9943.79 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)10.79

Net Charge (pH 7.4) 10.26

Charge Density (pH 7.0) 0.1226

GRAVY Index-0.26

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index51.58

Aliphatic Index 77.61

Aromaticity 0.0682

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3906.92

LogP -36.87

H-bond Donors 140.0

H-bond Acceptors 139.0

Rotatable Bonds 328.0

Heavy Atoms 692.0

Ring Count 17.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163304 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence