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MYP_134308
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Basic Information
F2.3S
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C72H126N20O19
Standard
Sequence
GLVGTLLGHIGKAILGG
Physicochemical Analysis
1575.89 Da
8.76
0.85
0.59
0.0498
1.18
0.50
0.57
38.86
160.59
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
603.85
-4.63
21.0
21.0
53.0
111.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017026 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human RBCs
6.25-200 μM
Hemolysis
PMID30044391 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30044391/
RECORD: Rec_0021622 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 36055
100 μM
ED50
PMID30044391 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30044391/
RECORD: Rec_0067857 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 39413
11.99±0.001 μM
ED50
PMID30044391 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30044391/
RECORD: Rec_0085000 VERIFIED: YES
Provenance & Taxonomy
Orinoco lime treefrog [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
it is not cytotoxic at 100 ug/ml to Vero E6 cells.
PaperFrog skin cultures secrete anti-yellow fever compounds
RECORD: Rec_0103429 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Ranacyclin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 34026
55.82±0.005
ED50
PMID30044391 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30044391/
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