Peptide Database

Peptide Namealpha-defensin 2 isoform X2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC435H709N127O147S11

DescriptionStandard

        MKPLVLLSALVLLSFQVQADPIQNTDEETKTEEQSGEEDQAVSVSFGDPEGSSLQEECEDLVCYCRTRGCKRRERMNGTCRKGHLMYMLCCR
    

Molecular Weight10422.76 Da

Isoelectric Point (pI)4.82

Net Charge (pH 7.0)-5.45

Net Charge (pH 7.4) -5.85

Charge Density (pH 7.0) -0.0593

GRAVY Index-0.54

Hydrophobic Moment 0.43

Boman Index-0.15

Instability Index60.02

Aliphatic Index 68.80

Aromaticity 0.0435

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4475.85

LogP -51.37

H-bond Donors 161.0

H-bond Acceptors 154.0

Rotatable Bonds 358.0

Heavy Atoms 720.0

Ring Count 8.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419571 VERIFIED: NO

Provenance & Taxonomy

OrganismMus caroli [Animal]

FamilyDefensin

Tax ID10089

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal