Peptide Database

Peptide NameGuanylate-binding protein 5 (EC 3.6.5.-) (GTP-binding protein 5) (GBP-5) (MuGBP-5) (Guanine nucleotide-binding protein 5)

Function Ontology

Antimicrobial

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length590 amino acids

Chemical FormulaC2939H4706N832O912S20

DescriptionStandard

        MAPEIHMPEPLCLIGSTEGHLVTNQEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKEKGFSVGSTVQSHTKGIWMWCVPHPQKPDHTLVLLDTEGLGDVEKDDKKNDTQIFALAILLSSTFVYNTMNKIDQGAIDLLHNVTELTDLLRTRNSSDSNQTEGEGPADMSFFPDLVWTLRDFFLDLQANGHAITSDEYLENSLKLKQGSDERTQTFNLPRLCIQKFFPVKKCFVFDAPALGSKLSQLPTLSNEELNSDFVQDLSEFCSHIFTQSKTKTLPGGIQVNGPRLESLVLTYVDAINSGALPSIENTVVTLARRENSAAVQKAIGHYDQLMSEKVQLPTETLQELLDLHRTCEREAIEIFRKHSFKDEGEFFQKELESLLSAKQDEICKKNADASAALCSTLLGSIFKPLEQEVAQEFYHKPGGHKLFLQRMEQLKANYRQQPGKGTQAEEVLQTYLNAKETVSRTILQTDQVLTDKEIQSKAEQERAEAARLEAQRLEAIRIQEEQRKAEMERQHQEQLRQIALEKARVAQEQQWILKQRAQEEADRIKAEQEAQLRALQQQLQHMREMNHHRRHHHDCVIS
    

Molecular Weight66929.13 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-14.71

Net Charge (pH 7.4) -16.25

Charge Density (pH 7.0) -0.0249

GRAVY Index-0.51

Hydrophobic Moment 0.70

Boman Index-0.08

Instability Index44.43

Aliphatic Index 86.98

Aromaticity 0.0593

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212344 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Hydrolase Non-hemolytic

TargetNo Target Organism Found

PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID12396730;19468303;15489334;18025219;22461501 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12396730/