Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length243 amino acids

Chemical FormulaC1231H1889N283O369S8

DescriptionStandard

        QIDDLAEVDYSLNSLPAVFRPFIDLDLKGVVFPAGNHTDSPYVAASFTIPDQSDSMLYLALSEYFFQTSSFAYYTAGAFNVTIAEEVTTHLFSLSFIFLQTCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNRIQFSLAHSNVGSFEILLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight26813.36 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-15.97

Net Charge (pH 7.4) -16.40

Charge Density (pH 7.0) -0.0657

GRAVY Index0.39

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index45.37

Aliphatic Index 105.14

Aromaticity 0.1193

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203403 VERIFIED: NO

Provenance & Taxonomy

OrganismDasyornis broadbenti [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria