Peptide Database

Peptide NameAntimicrobial peptide 1 (AamAP1) (Non-disulfide-bridged peptide 4.11) (NDBP-4.11)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC393H633N105O105S2

DescriptionStandard

        MEIKYLLTVFLVLLIGSDYCQAFLFSLIPHAIGGLISAFKGRRKRDLDGQIDRSRNFRKRDAELEELLSKLPIY
    

Molecular Weight8573.00 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.28

Charge Density (pH 7.0) 0.0350

GRAVY Index0.07

Hydrophobic Moment 0.48

Boman Index0.03

Instability Index37.97

Aliphatic Index 118.65

Aromaticity 0.1081

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3409.16

LogP -22.95

H-bond Donors 122.0

H-bond Acceptors 111.0

Rotatable Bonds 293.0

Heavy Atoms 605.0

Ring Count 11.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019551 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetCandida albicans

RECORD: Rec_0083230 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0368977 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)