Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC543H873N147O165S2

DescriptionStandard

        PDLSGHEKYGLGNVKYNISGIHITAVEIPSASISLIPGTGIKLVIGNASLTINTNWNIRTWMFKDSGRSTVYISKVFVTAIFSTTLDHTGHTSLALTSCRTTSGAIDIKLNGKS
    

Molecular Weight12164.76 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.30

Net Charge (pH 7.4) 4.00

Charge Density (pH 7.0) 0.0377

GRAVY Index0.10

Hydrophobic Moment 0.48

Boman Index0.16

Instability Index15.25

Aliphatic Index 99.21

Aromaticity 0.0702

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4986.75

LogP -57.08

H-bond Donors 180.0

H-bond Acceptors 175.0

Rotatable Bonds 401.0

Heavy Atoms 857.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326501 VERIFIED: NO

Provenance & Taxonomy

OrganismSemnornis frantzii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria