Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC406H639N105O136S13

DescriptionStandard

        MKTFASAVILAVALTICIEENAAFPFTTVSSLLDEEKSTDDPAAMQEETSVETWMMPFDIGENRDTSPVRCHHCCDCCLLSGCGICCQ
    

Molecular Weight9583.88 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-10.39

Net Charge (pH 7.4) -10.86

Charge Density (pH 7.0) -0.1180

GRAVY Index0.18

Hydrophobic Moment 0.41

Boman Index0.13

Instability Index59.79

Aliphatic Index 74.32

Aromaticity 0.0568

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3806.86

LogP -41.73

H-bond Donors 138.0

H-bond Acceptors 141.0

Rotatable Bonds 310.0

Heavy Atoms 660.0

Ring Count 12.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269996 VERIFIED: NO

Provenance & Taxonomy

OrganismHaplochromis burtoni [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal