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MYP_133924
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Basic Information
B1CTcu2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C125H204N30O26S
Standard
Sequence
FLPLLAGLAANFLPKIFCKITRK
Physicochemical Analysis
2575.21 Da
10.32
3.75
3.53
0.1629
0.88
0.78
0.29
12.40
131.74
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
889.22
-2.35
31.0
31.0
83.0
182.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0168104 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0233896 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
MRSA ATCC 43300
50 μg/mL
MIC
PaperNovel antibacterial peptides from the skin secretion of the Indian bicoloured frog Clinotarsus curtipes.
RECORD: Rec_0239103 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
10 μg/mL
MIC
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0277086 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0314474 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus MTCC 9542, Bacillus subtilis MTCC 14416
12.5 μg/mL
MIC
PaperNovel antibacterial peptides from the skin secretion of the Indian bicoloured frog Clinotarsus curtipes.
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