‹ ›
MYP_133911
← PREVIOUS NEXT → BACK
Basic Information
Antihypertensive peptide 2
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Renin inhibition ▸ Renin inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
4 amino acids
C21H32N4O8
Standard
Sequence
SVYT
Physicochemical Analysis
468.50 Da
5.24
-0.54
-0.75
-0.1352
0.35
0.30
0.28
-32.58
72.50
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
211.31
-2.17
8.0
8.0
12.0
33.0
1.0
3.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0017813 VERIFIED: NO
Provenance & Taxonomy
Cannabis sativa [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Antihypertensive
RECORD: Rec_0074470 VERIFIED: YES
Provenance & Taxonomy
Cannabis sativa [Plant]
3483.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
63.0
PaperGirgih AT, He R, Aluko RE.. Kinetics and molecular docking studies of the inhibitions of angiotensin converting enzyme and renin activities by hemp seed (Cannabis sativa L.) peptides. J. Agric. Food Chem. 62, 4135?4144, 2014.
RECORD: Rec_0186295 VERIFIED: YES
Provenance & Taxonomy
Cannabis sativa [Plant]
ACE inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
0.063 μM
IC50
PaperPubMed PMID 24766098 PMID24766098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24766098/
RECORD: Rec_0190118 VERIFIED: YES
Provenance & Taxonomy
Cannabis sativa [Plant]
3483.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperGirgih AT, He R, Malomo SA, Offengenden M, Wu J, Aluko RE.. Structural and functional characterization of hemp seed (Cannabis sativa L.) protein-derived antioxidant and antihypertensive peptides. J. Funct. Foods 6, 384-394.
RECORD: Rec_0373645 VERIFIED: YES
Provenance & Taxonomy
Cannabis sativa [Plant]
3483.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Renin inhibitory
Renin
PaperGirgih AT, He R, Malomo SA, Offengenden M, Wu J, Aluko RE.. Structural and functional characterization of hemp seed (Cannabis sativa L.) protein-derived antioxidant and antihypertensive peptides. J. Funct. Foods 6, 384-394.