Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC445H723N127O119S9

DescriptionStandard

        MKFLFLFLAILLATEVPVISVECWMDGHCRLLCKDGEDSIIRCRNRKRCCVPSRYLTIQPVTIHGILGWTTPQMSTTAPKTKRNIHNG
    

Molecular Weight10044.87 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.0649

GRAVY Index0.05

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index68.91

Aliphatic Index 95.23

Aromaticity 0.0682

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3934.33

LogP -34.07

H-bond Donors 145.0

H-bond Acceptors 137.0

Rotatable Bonds 329.0

Heavy Atoms 700.0

Ring Count 16.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105660 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0224353 VERIFIED: NO