Peptide Database

Peptide NameEndothelin 2

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC117H165N27O31S4

DescriptionStandard

        CSCSSWLDKECVWFCHLDIIW
    

Molecular Weight2573.98 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.1042

GRAVY Index0.52

Hydrophobic Moment 0.28

Boman Index0.27

Instability Index68.91

Aliphatic Index 88.10

Aromaticity 0.1905

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 919.98

LogP -4.05

H-bond Donors 37.0

H-bond Acceptors 34.0

Rotatable Bonds 78.0

Heavy Atoms 179.0

Ring Count 8.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392251 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Canis familiaris [Animal]

Tax ID9606, 9615

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Neuropeptide