MYP_133845
R6
Anticancer
Antimicrobial
Delivery / Targeting
▸
Cell penetration
▸
Cell-penetrating peptide
Delivery / Targeting
▸
Drug delivery vehicle
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
XRRRRRR
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0065946
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
FITC
Amidation
X=Beta-Alanine; C-terminal amidation
Bio-Activity Profile
Cellular uptake
Cargo delivery
cultured mammalian cells
flow cytometry and confocal microscopy cellular-uptake assay
RECORD: Rec_0387422
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Contains non-standard or unspecified residue(s): X; Conjugate type: amide; Conjugated small molecule: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-¦Á-L-lyxo-hexopyranosyl)oxy]-8-(1-hydrazonoethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-Naphthacenedione
Bio-Activity Profile
Anticancer
HL-60 human leukemia cells; HepG2 human hepatoma cells
MTT cytostasis assay; flow cytometry cellular-uptake assay