Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC595H947N163O166S3

DescriptionStandard

        SPQLQERYPELPMELQLSARRQPLLSCHPQALHGALFGSAEAFVVLPDATRVPAFLLDIDANVTGKPSIRGNRLGGTVKLTGVTQVTSRVGPVEVKRLETLLKFGLWLFGVPWANSEYCP
    

Molecular Weight13136.07 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)1.63

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0136

GRAVY Index-0.00

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index46.47

Aliphatic Index 99.08

Aromaticity 0.0750

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5202.24

LogP -46.68

H-bond Donors 179.0

H-bond Acceptors 173.0

Rotatable Bonds 419.0

Heavy Atoms 927.0

Ring Count 24.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028122 VERIFIED: NO

Provenance & Taxonomy

OrganismOreotrochilus melanogaster [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria