Peptide Database

Peptide NameSLAY-screened peptide P3337

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC100H165N27O25S

DescriptionStandard

        PKTASCVALPAILPRLAWVGN
    

Molecular Weight2177.61 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.87

Charge Density (pH 7.0) 0.0927

GRAVY Index0.69

Hydrophobic Moment 0.34

Boman Index0.29

Instability Index42.42

Aliphatic Index 120.95

Aromaticity 0.0476

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 801.01

LogP -5.97

H-bond Donors 29.0

H-bond Acceptors 28.0

Rotatable Bonds 64.0

Heavy Atoms 153.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087258 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/