Peptide Database

Peptide NameVascular endothelial growth factor B

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC830H1334N250O260S12

DescriptionStandard

        PVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAPSTTSALTPGPAAAAADAAASSVAKGGA
    

Molecular Weight19359.77 Da

Isoelectric Point (pI)7.98

Net Charge (pH 7.0)1.51

Net Charge (pH 7.4) 0.95

Charge Density (pH 7.0) 0.0081

GRAVY Index-0.37

Hydrophobic Moment 0.53

Boman Index-0.01

Instability Index51.14

Aliphatic Index 64.57

Aromaticity 0.0215

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7933.04

LogP -104.10

H-bond Donors 274.0

H-bond Acceptors 280.0

Rotatable Bonds 598.0

Heavy Atoms 1352.0

Ring Count 38.0

Amide Bonds 196.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0385183 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPDGF/VEGF growth factor family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide26-68; 57-101; 61-103

Bio-Activity Profile

Function

Cytokine Growth factor PDGF VEGF growth factor family Chemoattractant Growth factor signaling Angiogenic Heparin-binding