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MYP_133744
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Basic Information
Feleucin-K65
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XLKLLKKLL
Physicochemical Analysis
0.00 Da
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033814 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Alpha-(4-pentenyl)-Ala, C-terminal: NH2 at 1; Alpha-(4-pentenyl)-Ala, C-terminal: NH2
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA 48
4 μg/mL
MIC
PMID34069651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34069651/
RECORD: Rec_0059899 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Alpha-(4-pentenyl)-Ala, C-terminal: NH2 at 1; Alpha-(4-pentenyl)-Ala, C-terminal: NH2
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC27853
8 μg/mL
MIC
PMID34069651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34069651/
RECORD: Rec_0088828 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Alpha-(4-pentenyl)-Ala, C-terminal: NH2 at 1; Alpha-(4-pentenyl)-Ala, C-terminal: NH2
Bio-Activity Profile
Hemolytic
mouse red blood cells
128 μg/mL
Hemolysis
PMID34069651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34069651/
RECORD: Rec_0114865 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Alpha-(4-pentenyl)-Ala, C-terminal: NH2 at 1; Alpha-(4-pentenyl)-Ala, C-terminal: NH2
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC19606
4 μg/mL
MIC
PMID34069651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34069651/
RECORD: Rec_0156862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Alpha-(4-pentenyl)-Ala, C-terminal: NH2 at 1; Alpha-(4-pentenyl)-Ala, C-terminal: NH2
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA ATCC33591
4 μg/mL
MIC
PMID34069651 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34069651/
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