Peptide Database

Peptide NameSLAY-screened peptide P3569

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC71H108N24O20

DescriptionStandard

        YHGRLSPVSFNRNA
    

Molecular Weight1617.77 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.1319

GRAVY Index-0.82

Hydrophobic Moment 0.34

Boman Index-0.18

Instability Index64.65

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 732.18

LogP -9.02

H-bond Donors 26.0

H-bond Acceptors 23.0

Rotatable Bonds 49.0

Heavy Atoms 115.0

Ring Count 4.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005393 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/