Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length359 amino acids

Chemical FormulaC1797H2817N457O526S17

DescriptionStandard

        GKRIGMELLKEAILKESFPSWSGQESFAFVKVNYRISGLRINTVDFPETSASFIPGTGISLSVTRASATMSADWGLKTWLLENCCSFPPSQFSCPSIFSHLSSSSESSFFTISKMPLPLAKQLQVLICFCNNIHFVLSIILLVLSQIDAFAQIDYSLVSSPAVFKSHLNLDLKVIFYAVGNHRDPPFMPAPFALPNQGDSMLYLGVSNYFLKSASLAYYKAGIFNLTISQEVEVSRVRKQQSEALRMVQSRNLPYGTGESQSDLRLMATETPIISLQQDSFTLEIQGSMEVFAVLPDSSTQSLFTMSIVSMMKEATIHSDLNVFISLLENILSYILQTEVIPSANGEAAFLMTRHRGRL
    

Molecular Weight39784.44 Da

Isoelectric Point (pI)6.11

Net Charge (pH 7.0)-2.73

Net Charge (pH 7.4) -3.38

Charge Density (pH 7.0) -0.0076

GRAVY Index0.19

Hydrophobic Moment 0.63

Boman Index0.16

Instability Index54.27

Aliphatic Index 97.24

Aromaticity 0.1003

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0000070 VERIFIED: NO

Provenance & Taxonomy

OrganismNothoprocta perdicaria [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence