Peptide Database

Peptide NameVGLP1K6 (Glucagon like peptide 1 derivative)

Function Ontology

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC184H293N51O52S2

DescriptionStandard

        HAEGTFTSDVSCYLEGQAACEFIAWLVKGRGKKKKKK
    

Molecular Weight4115.74 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)3.83

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.1035

GRAVY Index-0.57

Hydrophobic Moment 0.44

Boman Index-0.10

Instability Index27.13

Aliphatic Index 58.11

Aromaticity 0.1081

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1692.87

LogP -15.86

H-bond Donors 62.0

H-bond Acceptors 59.0

Rotatable Bonds 143.0

Heavy Atoms 289.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0300645 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGLP-1

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide12-20

Bio-Activity Profile

Function

Antihyperglycemic Metabolic regulation

MethodELISA

Half-LifeDPP IV, in vitro; ~252000 s