Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC155H234N42O43S2

DescriptionStandard

        AANQHLCGSHLVEALYLVCGERGFFYTPNKV
    

Molecular Weight3437.90 Da

Isoelectric Point (pI)6.94

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0015

GRAVY Index0.15

Hydrophobic Moment 0.46

Boman Index0.18

Instability Index14.75

Aliphatic Index 88.06

Aromaticity 0.1290

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1357.60

LogP -11.76

H-bond Donors 48.0

H-bond Acceptors 47.0

Rotatable Bonds 108.0

Heavy Atoms 242.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0005286 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [Animal]

FamilyInsulin

Tax ID7902

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0342054 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0411390 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [Animal]

FamilyInsulin

Tax ID7902

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour