Peptide Database

Peptide NameSLAY-screened peptide P4891

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H124N28O20

DescriptionStandard

        ARNALGLFHNYRHQL
    

Molecular Weight1810.03 Da

Isoelectric Point (pI)10.84

Net Charge (pH 7.0)1.97

Net Charge (pH 7.4) 1.68

Charge Density (pH 7.0) 0.1313

GRAVY Index-0.65

Hydrophobic Moment 0.49

Boman Index-0.13

Instability Index34.91

Aliphatic Index 91.33

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 801.38

LogP -7.34

H-bond Donors 28.0

H-bond Acceptors 24.0

Rotatable Bonds 58.0

Heavy Atoms 129.0

Ring Count 4.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205499 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/