Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC704H1138N196O210S4

DescriptionStandard

        MKLSNNGVAFIKREEGEKLTAYADSVGVLTIGVGHTGAVSGKPITRGMTITQNQSTALLLSDLAWVESSIGKSVKVPLTQNQYDALCSFVFNVGKSAFENSTLLKKLNACDYAGAADQFLQWKRAGNIPDLLLPRRKRERELFKT
    

Molecular Weight15836.01 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)5.58

Net Charge (pH 7.4) 5.25

Charge Density (pH 7.0) 0.0385

GRAVY Index-0.18

Hydrophobic Moment 0.51

Boman Index0.02

Instability Index26.98

Aliphatic Index 90.83

Aromaticity 0.0759

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6598.04

LogP -69.62

H-bond Donors 231.0

H-bond Acceptors 221.0

Rotatable Bonds 537.0

Heavy Atoms 1114.0

Ring Count 18.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020446 VERIFIED: YES

Provenance & Taxonomy

OrganismErwinia phage vB_EhrS_49 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0194274 VERIFIED: YES