Peptide Database

Peptide NameDNA dC->dU-editing enzyme APOBEC-3F

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length373 amino acids

Chemical FormulaC2067H2995N535O557S24

DescriptionStandard

        MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
    

Molecular Weight45019.70 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.0015

GRAVY Index-0.50

Hydrophobic Moment 0.90

Boman Index-0.03

Instability Index37.05

Aliphatic Index 61.18

Aromaticity 0.1877

Extinction Coeff. Reduced 121240.00

Extinction Coeff. Oxidized 122115.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228482 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyAPOBEC

Tax ID9606

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide280-283

Bio-Activity Profile

Function

Antiviral Release inhibition Budding inhibition Replication inhibitor Anti-XMRV

TargetXenotropic murine leukemia virus-related virus (XMRV)

RECORD: Rec_0413614 VERIFIED: YES