Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC923H1401N211O281S6

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPFIDLDLKGIVYPAGNYTGPPYVAAPFTIPDQSDSMLHLAFSEYFFQTSSFAYYTAGAFSITIAEETCSYFNISTEIFGSIIPEVAKYSVTRYPVMLKLTATEIPIISLEQDSFTVEIRGSMEVFAVLPDSSTQSLFTVNVAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight20141.63 Da

Isoelectric Point (pI)4.08

Net Charge (pH 7.0)-13.15

Net Charge (pH 7.4) -13.47

Charge Density (pH 7.0) -0.0718

GRAVY Index0.31

Hydrophobic Moment 0.55

Boman Index0.24

Instability Index39.92

Aliphatic Index 95.96

Aromaticity 0.1311

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7777.58

LogP -83.42

H-bond Donors 266.0

H-bond Acceptors 275.0

Rotatable Bonds 638.0

Heavy Atoms 1421.0

Ring Count 36.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346667 VERIFIED: NO

Provenance & Taxonomy

OrganismHaliaeetus albicilla (White-tailed sea-eagle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria