Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC963H1546N268O265S7

DescriptionStandard

        PTTLPVAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELQLWARQQPLLSCHPDALHGTLLSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELGLSSPRTRAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPPAVP
    

Molecular Weight21342.67 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)7.21

Net Charge (pH 7.4) 6.93

Charge Density (pH 7.0) 0.0372

GRAVY Index-0.02

Hydrophobic Moment 0.57

Boman Index0.06

Instability Index61.04

Aliphatic Index 96.03

Aromaticity 0.0670

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8398.04

LogP -105.55

H-bond Donors 289.0

H-bond Acceptors 282.0

Rotatable Bonds 674.0

Heavy Atoms 1503.0

Ring Count 40.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333393 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodinocichla rosea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria