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MYP_133476
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Basic Information
Temporin-SHc
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
13 amino acids
C72H104N16O17
Standard
Sequence
FLSHIAGFLSNLF
Physicochemical Analysis
1465.69 Da
6.74
-0.15
-0.41
-0.0117
1.34
0.43
0.59
43.03
127.69
0.2308
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
524.75
-2.39
18.0
18.0
45.0
105.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0227515 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 38.5%, E 0.0%, T 38.5%, C 23.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0230914 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 90028
20 μM
MIC
PaperIsolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica.
RECORD: Rec_0236014 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
A. flavus
10 μM
MIC
PaperIsolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica.
RECORD: Rec_0249357 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 35218
>80 μM
MIC
PaperIsolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica.
RECORD: Rec_0253102 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
10 μM
MIC
PaperIsolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica.
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