‹ ›
MYP_133476
← PREVIOUS NEXT → BACK
Basic Information
Temporin-SHc
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
13 amino acids
C72H104N16O17
Standard
Sequence
FLSHIAGFLSNLF
Physicochemical Analysis
1465.69 Da
6.74
-0.15
-0.41
-0.0117
1.34
0.43
0.59
43.03
127.69
0.2308
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
524.75
-2.39
18.0
18.0
45.0
105.0
4.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0007342 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0022645 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Saccharomyces cerevisiae
10 μM
MIC
PMID18584916 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18584916/
RECORD: Rec_0036085 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
80.0 μM
HC50
PaperF. Abbassi et al. / Peptides 29 (2008) 1526-1533. Isolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica
RECORD: Rec_0051420 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 90028
20 μM
MIC
PMID18584916 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18584916/
RECORD: Rec_0057895 VERIFIED: YES
Provenance & Taxonomy
Sahara frog [Animal]
Temporin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18584916 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18584916/
1 2 3 ... 7 NEXT LAST
Showing 5 records on this page · Page 1 of 7