Peptide Database

Peptide NameSLAY-screened peptide P1623

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC49H72N14O14

DescriptionStandard

        ATIYAHYRS
    

Molecular Weight1081.18 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)0.88

Net Charge (pH 7.4) 0.64

Charge Density (pH 7.0) 0.0979

GRAVY Index-0.41

Hydrophobic Moment 0.26

Boman Index-0.00

Instability Index104.62

Aliphatic Index 65.56

Aromaticity 0.2222

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 467.62

LogP -4.14

H-bond Donors 18.0

H-bond Acceptors 16.0

Rotatable Bonds 31.0

Heavy Atoms 77.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185659 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/