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MYP_133454
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Basic Information
U1-poneritoxin-Da4a (U1-PONTX-Da4a) (Dinoponeratoxin Da-3105) (Poneratoxin)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
28 amino acids
C141H228N40O37S
Standard
Sequence
GLKDWWNKHKDKIIAVAKEMGKAGLQAA
Physicochemical Analysis
3107.63 Da
9.70
2.85
2.58
0.1017
-0.55
0.54
-0.03
30.48
83.93
0.0714
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1263.48
-8.78
43.0
42.0
109.0
219.0
5.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113055 VERIFIED: YES
Provenance & Taxonomy
Dinoponera australis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Toxin Hemolytic Insecticidal
Gram-negative and Gram-positive bacteria
PaperThe Biochemical Toxin Arsenal from Ant Venoms PMID19879289;26805882 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19879289/
RECORD: Rec_0175867 VERIFIED: NO
Provenance & Taxonomy
Dinoponera australis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0212208 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 10.7%, E 7.1%, T 53.6%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0273730 VERIFIED: YES
Provenance & Taxonomy
Dinoponera australis [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 19879289 PMID19879289 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19879289/