Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length729 amino acids

Chemical FormulaC3415H5341N933O1067S20

DescriptionStandard

        MTRIMSTMLYIHPPHGCCAFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDQTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFTRAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPVYVMLSGPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGELPDNKVMIDRLENILNGGLQATDTDLRFYTHEIRELERYRNLGVKDGVIPDNYDEVWNNTHTATLEDYKINEKTQPLYTPEAEEAYRKAEEGK
    

Molecular Weight77180.85 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-29.01

Net Charge (pH 7.4) -30.27

Charge Density (pH 7.0) -0.0398

GRAVY Index-0.28

Hydrophobic Moment 0.77

Boman Index0.07

Instability Index34.64

Aliphatic Index 77.02

Aromaticity 0.0645

Extinction Coeff. Reduced 76780.00

Extinction Coeff. Oxidized 76905.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223132 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli