Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H873N149O166S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRMHVTAVELPSASISLLPSSGIKLVIGNASLTINMNWNIRTWMFKDSGRGTVHLSKVFVTAIFSTPLDNTGPTSISLTSCQTTSGDVDITLNGKR
    

Molecular Weight12248.88 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.00

Hydrophobic Moment 0.52

Boman Index0.11

Instability Index25.17

Aliphatic Index 92.28

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5039.16

LogP -59.31

H-bond Donors 179.0

H-bond Acceptors 176.0

Rotatable Bonds 403.0

Heavy Atoms 860.0

Ring Count 17.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261771 VERIFIED: NO

Provenance & Taxonomy

OrganismDasyornis broadbenti [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria