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MYP_133405
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Basic Information
Ponericin G7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C88H158N22O22
Standard
Sequence
GLVDVLGKVGGLIKKLLPG
Physicochemical Analysis
1876.33 Da
9.70
1.76
1.55
0.0925
0.91
0.55
0.37
-4.15
168.95
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
693.69
-3.11
23.0
24.0
65.0
132.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016764 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Insecticidal
Gram-positive and Gram-negative bacteria; Saccharomyces cerevisiae; cricket larvae; erythrocytes
agar-well diffusion antimicrobial/antifungal assay; insecticidal assay; hemolysis assay
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0040645 VERIFIED: YES
Provenance & Taxonomy
Neoponera goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
Gram-positive and Gram-negative bacteria; Saccharomyces cerevisiae; cricket larvae; erythrocytes
agar-well diffusion antimicrobial/antifungal assay; insecticidal assay; hemolysis assay
PaperJ. Biol. Chem. 2001; 276: 17823-17829. PubMed. | http://www.ncbi.nlm.nih.gov/pubmed/11279030 PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0059726 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10 peptide-expressing strain
3.84 OD_ID (dimensionless)
MeX pooled intracellular peptide-expression growth-inhibition assay (NGS-derived OD_ID at 4.5 h)
PaperKoch P et al. Discovery of antimicrobials by massively parallelized growth assays (MeX). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0070897 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]; Insecta [Animal]
Ponericin
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Gram-positive and Gram-negative bacteria; Saccharomyces cerevisiae; cricket larvae; erythrocytes
agar-well diffusion antimicrobial/antifungal assay; insecticidal assay; hemolysis assay
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0109529 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
has activity against Gram-positive bacteria and S
agar-well diffusion antimicrobial/antifungal assay; insecticidal assay; hemolysis assay
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9. doi: 10.1074/jbc.M100216200. PMID: 11279030. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
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