Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC74H130N32O21S

DescriptionStandard

        GSRVQIRCRFRNSTR
    

Molecular Weight1836.09 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.53

Charge Density (pH 7.0) 0.3167

GRAVY Index-1.21

Hydrophobic Moment 0.55

Boman Index-0.68

Instability Index30.40

Aliphatic Index 45.33

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 927.09

LogP -13.49

H-bond Donors 37.0

H-bond Acceptors 27.0

Rotatable Bonds 63.0

Heavy Atoms 128.0

Ring Count 1.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283746 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0330374 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHSV

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0414389 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyVirus-derived peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetHerpes simplex virus 1 (Virus entry); GMK

Activity19 μM

MethodPlaque assay

PaperStructural and functional features of the polycationic peptide required for inhibition of herpes simplex virus invasion of cells. | Trybala E, Olofsson S, Mardberg K, Svennerholm B, Umemoto K, Glorioso JC, Bergstrom T. | Antiviral Res. 2004 | PMID:15130536 PMID15130536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15130536/