Peptide Database

Peptide NameGassericin A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC261H411N67O72S

DescriptionStandard

        IYWIADQFGIHLATGTARKLLDAMASGASLGTAFAAILGVTLPAWALAAAGALGATAA
    

Molecular Weight5671.53 Da

Isoelectric Point (pI)6.75

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0026

GRAVY Index1.00

Hydrophobic Moment 0.56

Boman Index0.46

Instability Index3.73

Aliphatic Index 116.72

Aromaticity 0.0862

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2140.94

LogP -18.38

H-bond Donors 76.0

H-bond Acceptors 74.0

Rotatable Bonds 176.0

Heavy Atoms 401.0

Ring Count 9.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024893 VERIFIED: YES

Provenance & Taxonomy

OrganismBacteria [Bacterium]

Tax ID2

Structure & Mods

Confighead-to-tail cyclic bacteriocin [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermHead-to-tail cyclized to C terminus

C-TermHead-to-tail cyclized to N terminus

Other ModsN-to-C backbone cyclization

Bio-Activity Profile

Function

Antimicrobial

TargetGram-positive food-borne bacteria including Lactobacillus reuteri LA6

Methodbacteriocin growth-inhibition/activity-spectrum assay

RECORD: Rec_0136757 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus gasseri [Bacterium]

FamilyBacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermHead-to-tail cyclized to C terminus

C-TermHead-to-tail cyclized to N terminus

Other ModsN-to-C backbone cyclization

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetGram-positive food-borne bacteria including Lactobacillus reuteri LA6

Methodbacteriocin growth-inhibition/activity-spectrum assay

RECORD: Rec_0157923 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus gasseri [Bacterium]

Structure & Mods

Confighead-to-tail cyclic bacteriocin [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermHead-to-tail cyclized to C terminus

C-TermHead-to-tail cyclized to N terminus

Other ModsN-to-C backbone cyclization

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetGram-positive food-borne bacteria including Lactobacillus reuteri LA6

Methodbacteriocin growth-inhibition/activity-spectrum assay

RECORD: Rec_0210458 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus reuteri [Bacterium]

FamilyBacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermHead-to-tail cyclized to C terminus

C-TermHead-to-tail cyclized to N terminus

Other ModsN-to-C backbone cyclization

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetGram-positive(certain)

Methodbacteriocin growth-inhibition/activity-spectrum assay

RECORD: Rec_0402105 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus gasseri [Bacterium]

FamilyBacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermHead-to-tail cyclized to C terminus

C-TermHead-to-tail cyclized to N terminus

Other ModsN-to-C backbone cyclization

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

Targetreuteri LA6

Methodbacteriocin growth-inhibition/activity-spectrum assay