Peptide Database

Peptide NameCycloviolacin O25

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC121H196N32O37S6

DescriptionStandard

        CGESCVWIPCISSVVGCSCKSKVCYKN
    

Molecular Weight2883.43 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0629

GRAVY Index0.50

Hydrophobic Moment 0.34

Boman Index0.15

Instability Index32.31

Aliphatic Index 71.85

Aromaticity 0.0741

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1106.75

LogP -13.17

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 92.0

Heavy Atoms 196.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354038 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)