Peptide Database

Peptide NameLEDGF-(360-70)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC59H93N15O19

DescriptionStandard

        WNSLKIDNLDV
    

Molecular Weight1316.46 Da

Isoelectric Point (pI)4.21

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1126

GRAVY Index-0.30

Hydrophobic Moment 0.07

Boman Index0.03

Instability Index4.87

Aliphatic Index 132.73

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 577.14

LogP -4.41

H-bond Donors 19.0

H-bond Acceptors 18.0

Rotatable Bonds 43.0

Heavy Atoms 93.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188866 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetHIV-1[80-90% IN activity = 19.5 microM

RECORD: Rec_0274941 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

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