Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC421H669N121O125S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICMLESSAIPFAGVQEPEEAGSNDTPVVAHQEMSAESSMMPNHIRQKRQSHLSLCRWCCNCCRSNKGCGFCCKF
    

Molecular Weight9874.46 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0076

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.08

Instability Index74.17

Aliphatic Index 68.33

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3920.15

LogP -43.92

H-bond Donors 143.0

H-bond Acceptors 143.0

Rotatable Bonds 325.0

Heavy Atoms 681.0

Ring Count 14.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267293 VERIFIED: NO

Provenance & Taxonomy

OrganismCoptodon zillii [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal