Peptide Database

Peptide NameS19

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC161H272N60O35S

DescriptionStandard

        FTILEEYFMYRGLLGLRIRRRRRRRRR
    

Molecular Weight3640.33 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.3246

GRAVY Index-1.07

Hydrophobic Moment 0.47

Boman Index-0.66

Instability Index205.05

Aliphatic Index 86.67

Aromaticity 0.1481

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1636.11

LogP -12.32

H-bond Donors 66.0

H-bond Acceptors 45.0

Rotatable Bonds 127.0

Heavy Atoms 257.0

Ring Count 4.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064056 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays