Peptide Database

Peptide NameDefensin 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC353H590N104O99S11

DescriptionStandard

        MERKTLSLLFMLFLLLAADVTVKKADALLGRCKVKSSRYTGPCLTDTKCSTVCRGEGYKGGDCHGFRRRCMCLC
    

Molecular Weight8227.81 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)7.51

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.1015

GRAVY Index0.03

Hydrophobic Moment 0.52

Boman Index-0.06

Instability Index28.64

Aliphatic Index 79.05

Aromaticity 0.0676

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3289.51

LogP -33.16

H-bond Donors 129.0

H-bond Acceptors 119.0

Rotatable Bonds 281.0

Heavy Atoms 567.0

Ring Count 7.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044471 VERIFIED: NO

Provenance & Taxonomy

OrganismLens culinaris [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal